Biotechnology
Human Papillomavirus microRNA diagnostics and therapeutics
Uses of a p53 specific microRNA (miRNA): It has been reported that the tumor suppressive mRNA miR-34a (a downstream target of p53) is downregulated in HPV-infected primary keratinocytes
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Central Nervous System
A genetic diagnostic test for 'early-onset Alzheimer's disease'
SNP's in the human act gene correlates well with susceptibility to early-onset Alzheimer's Disease. Researchers have developed a test that could determine the presence of SNP's, which would allow therapeutic treatments to begin early
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Dermatological
Atopiclair - innovative non-steroidal cream for atopic dermatitis
New cream formulation to manage the symptoms of atopic dermatitis
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Diagnostic
Human and improved murine monoclonal antibodies against CD22
Two anti-CD22 antibodies of human origin have been generated; each has the ability to recognize CD22 on the surface of Raji cells
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Segmenting colon wall via level set techniques
A level set based method to determine, from a CT colonography (CTC) scan, the location of the colon serosal tissue boundary: After determining this location, the algorithm segments the entire colon wall at subvoxel accurate precision
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Drug discovery
Microarray binding sensors using carbon nanotube transistors
Unique distinctions of this design over other CNT based methods: complete isolation of the CNTs from chemical reactions concomitant with probe immobilization and target capture, and the CNTs functioning only as charge sensors
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Gastrointestinal
GL1001
GL1001 is a novel, clinical-stage small molecule drug candidate for the treatment of inflammatory diseases of the gastrointestinal tract
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Genito-urinary
Therapy for nephrogenic systemic fibrosis and scleroderma: Rapamycin inhibition of the phospho-70-ribosomal S6-kinase (08-23)
New use of rapamycin to treat nephrogenic systemic fibrosis and scleroderma
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Immune related disorders
LPCN 1019: Immunosuppressant ANDA opportunity
Immunosupressant product, bioequivalent to reference product
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Infectious diseases
Treatment to destroy virus particles
Academics at the University of Nottingham have invented a new method to inactivate viruses without affecting valuable blood and plasma proteins
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Musculoskeletal
BIS010, Semi-synthetic polysaccharide for the treatment of musculoskeletal and chronic inflammatory disorders including osteoarthritis and cartilage degeneration
BIS010 is a semi-synthetic plant origin polysaccharide demonstrating a potential modifying effect of the biologic activity of the joints
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Cartisorb ® (Glucosamine Sulfate sachets) - CTD dossier ready for registration
BIOIBERICA would extend the right to use its CTD dossier for registration of Cartisorb® (Glucosamine Sulfate sachets) as a branded generic drug (to be marketed under Cartisorb® brand name or other brand name) on a local level
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Oncology
Human monoclonal antibody against mesothelin
An anti-mesothelin antibody of human origin has been generated; it has the ability to efficiently recognize mesothelin on the surface of cells, and induce ADCC in mesothelin-positive cells
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Respiratory
LPCN 1035: Longer acting version of a leading respiratory product
LPCN 1035 is being developed as a longer acting version of a leading respiratory product, specifically as a non-sedating, non-narcotic anti-tussive
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