Press releases

Antony, France; Copenhagen, Denmark (May 14, 2007)– STALLERGENES SA and CMC Biopharmaceuticals A/S announce today that they have entered into an agreement for development and supply of rcombinant Bet v 1 (rBet v 1) purified bulk.

Bet v 1 is the protein that embodies most of the allergenicity of birch pollen, so called the major allergen of birch pollen.

CMC Biopharmaceuticals will scale up the manufacturing of GMP purified recombinant Bet v 1 and produce batches for Phase III clinical trials and commercial supply.

“CMC will allow us to benefit not only from its experienced management and its state-of- the-art fermentation facilities but also from its compliance with EMEA1 and FDA2 requirements”, said Albert Saporta, Chairman and CEO of STALLERGENES. “This agreement will speed our ORALAIR® Bet v 1 project towards late stage clinical trials and registration while securing the supply of active ingredients for commercial batches”.

“CMC is pleased to establish such a partnership with STALLERGENES in this truly innovative field of recombinant allergens; It is also a great opportunity to leverage our cGMP manufacturing capabilities with the short term prospect of an EMEA / FDA registration of a tablet for desensitization” said Mads Laustsen, CEO of CMC Biopharmaceuticals.

About ORALAIR® Bet v 1

According to World Health Organization (WHO) estimates, 20% to 25% of the world population is suffering from respiratory allergic symptoms, rhinitis and/or asthma.

Birch pollen is a major cause of those allergic symptoms, especially in the Northern countries of the Northern hemisphere. For instance, in Germany, up to 16% of the patients are sensitized to birch pollen.

1EMEA: European Agency for the Evaluation of Medicinal Products

2 FDA: Food and Drug Administration

STALLERGENES is a European biopharmaceutical company dedicated to desensitization therapies for the prevention and treatment of allergy-related respiratory diseases, e.g. rhino-conjunctivitis and allergic asthma.

Pioneer and leader in sublingual desensitization treatments, STALLERGENES devotes more than 15% of its sales to Research and Development and is fully involved in the development of a new therapeutic class, the sublingual desensitization tablets.

Headquarted in France, STALLERGENES markets its products through its subsidiaries or joint-ventures in Europe and through distribution agreements in other countries. In 2006, STALLERGENES reached a turnover of 126.6 million euros, mainly achieved in the European markets.

STALLERGENES is listed on the Eurolist Compartment B of the Euronext Paris Stock Exchange.

ISIN Code:FR0000065674

Reuters Code:GEN.PA

Bloomberg Code: GEN.FP

Additional information is available on http://www.stallergenes.com

Based in Copenhagen, Denmark, CMC is a contract development and manufacturing organization with sales offices located in both Europe and the U.S.

CMC specializes in process and analytical development as well as the scale-up and cGMP manufacture of Active Pharmaceutical Ingredients for pre-clinical, clinical trials and in-market production. CMC’s competitive strength is centered on the flexibility it can offer to customers combined with the extensive experience of its management and key personnel in the field of biopharmaceutical manufacture and development.

Additional information is available on www.cmcbio.com

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