Press releases

Release issued 18th December 2003

Postec(TM) - PRESS RELEASE

Scientific data shows that Postec (TM), an innovative and exclusive topical association of steroid betamethasone and hyaluronidase enzyme is safer and more efficacious than isolated topical steroid in the non surgical treatment of phimosis in children and adults (90 % vs. 70%)1-3 due to the synergistic action of betamethasone and hyaluronidase enzyme.

Postec (TM), developed and patented by Apsen Farmacêutica, was introduced in the Brazilian Market in the 2nd quarter of 2003.

References :

1.Palma PCR, Dambros M, Betametasona associada a hialuronidadase: uma alternativa eficaz no tratamento conservador da fimose Urologia Panamericana, Revista Oficial de la Confederación Americana de Urologia, vol 13, no 1, Enero -Marzo 2001.

2. Peyri M, El valerato de betametasona tópico em dermatologia, Actas Dermo-Sifiliografias, 27-36,1966.

3.Kikiros CS, Beasley SW, Woodward AA, The response of phimosis to local steroid application, Pediatr Surg Int (1993) 8:329-332.

COMPANY NAME AND ADDRESS

Apsen Farmacêutica S/A

Rua La Paz, no 37/67 - Santo Amaro

Zip code : 4755-020 São Paulo - SP - Brazil

COMPANY PROFILE - APSEN

Apsen Farmacêutica is a Brazilian pharmaceutical company with a history of commitments and achievements, made during the last four decades .

Our history goes hand in hand with the lives of thousands of people who have benefited from Apsen products significantly improving their quality of life.

Present in people´s daily lives

Our company manufactures products for a number of different indications, in specialties including urology, rheumatology, gynecology, neurology and others. Among such products Hyalozima, made with hyaluronidase, an own-manufactured purified enzyme (Apsen has exclusivity for the Brazilian market), deserves a special note. Product diversity combined with high technology manufacturing makes Apsen synonymous with high quality.

Rules are rules

The quality standards established internationally for the manufacturing of medicines are carefully complied with at Apsen. Manufactured products follow the GMP (Good Manufacturing Practices) standards. We use validated raw materials and adjuvants, skilled and trained technicians, high technology and monitored equipment, and strict control the whole manufacturing process. Appropriate quality assurance procedures, ensure that all procedures are according to our SOPs.

The future will be our biggest achievement

One of Apsen´s major qualities is launching, in Brazil, specific products to treat a wide range of diseases. Furthermore, we also look for new indications for traditional products already lunched. Physicians' and patients' positive response to this work philosophy has always justified Apsen's investment of time and financial resources. People win, physicians win, and we win the future.

See our full profile on Pharmalicensing at:

http://pharmalicensing.com/company/dc/2070

CONTACTS

Carlos Alberto M. Paris, MD

Medical Director

Apsen Farmacêutica S.A.

Phone: 00 55 11 5642 0085 - Extension 218