Name of the inventor: Jonathan M. Barasch A method of inducing the kidney epithelium formation is described. Methods of treating a subject with kidney failure, preserving a kidney for transplantation purposes are also proposed. The method involves...

Name of the inventor:
Jonathan M. Barasch A method of inducing the kidney epithelium formation is described. Methods of treating a subject with kidney failure, preserving a kidney for transplantation purposes are also proposed.

The method involves bringing mesenchymal precursor cells into contact with purified gpl30 receptor ligands in the presence of a growth factor.The regenerated kidney epithelium may then be transplanted into a subject with diminished kidney function. Effective kidney epithelium formation by signaling through the gp130 receptors has been elucidated.

Early Stage

Publication #: WO 00/66147 AU200049934-A

App. #: 09/305,029 PCT/US00/12536 00932171.2 09/980,853 AU200049934-A

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