Name of the inventor: Taka-aki Sato A composition capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein is described. A method of identifying a compound capable of inhibiting specific binding between a...

Name of the inventor: Taka-aki Sato A composition capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein is described. A method of identifying a compound capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein is also disclosed. The composition in effective amounts may be used to induce apoptosis in cancer cells and thereby inhibit the spread of cancer. The composition also finds use in inducing apoptosis in virus infected cells. Compositions that can serve as effective signal mediators of apoptosis have been disclosed.

Pat. Title: COMPOUNDS THAT INHIBIT THE INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS & THE GLGF (PDZ/DHR) DOMAIN & USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINSAND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS AND THE GLGF (PDZ/DHR) DOMAIN AND USES THEREOF COMPOUNDS THAT INHIBIT THE INTERACTION BETWEEN SIGNAL-TRANSDUCING PROTEINS & THE GLGF (PDZ/DHR) DOMAIN & USES THEREOF

Publication #: 02-0058607-A1 WO 98/05347 AU9740424-A CN1230120-A EP935467-A1 EP935467-A1 (EPO) JP2001505540-W KR2000029469-A MX9900599-A1 US 2003-0203414 A1

App. #: 08/681,219 PCT/US97/12677 40424/97 97197769 2260742 97937999.7 100984.8 507935/98 10-1999-700466 9900599 09/230,111 10-1999-7000466

Patent #: 6,911,526 735287 ZL97197769.0

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