Summary
Micelles are often used for drug delivery; however, there is a need for improved compositions Researchers at The University of Nebraska Medical Center have developed novel micelles by creating amphiphilic block copolymers that have a large solubility difference between the hydrophilic and hydrophobic blocks that assemble in aqueous solutions into polymer micelles of nanoscale size. The micelles can be used to encapsulate drugs or biological agents for improved delivery of the therapeutic agent. The novel micelle composition combines several structural features which improve the micelle’s capacity for drug delivery as compared to existing polymer micelle drug delivery compositions.

Market Value
Use in hospitals world-wide for improvment of drug delivery. May be used widely in cancer research/treatment.


Features and Benefits

• Improved Therapeutic Index
• Increased Stability and Solubility
• Wide Range of Deliverable Biological Agents
• Increased Bioavailability
• Permeable to Membranes and Biological Barriers

Application Published (US-2004-228823-A1)

(TID - 28)

UNeMed Corporation offers a variety of licensing options and collaborative development opportunities with the University of Nebraska Medical Center.