Out-licensing

Multiplex PCR based assay for the combined detection and diagnosis of Herpes viruses in patient samples.

Summary

Herpes viruses including Herpes Simplex (HSV), Cytomegalovirus (CMV), Varicella Zoster virus (VZV), Human Herpesvirus 6 (HHV6), and Epstein Barr Virus (EBV) are responsible for the common and significant viral infections associated with neonatal meningitis (HSV), adult meningitis (HSV or VZV), shingles (VZV), complications in solid organ transplant (CMV and EBV) and complications in bone marrow transplantation (CMV, EBV, HHV6).Researchers at the
University Nebraska Medical Center (UNMC) have developed a multiplex PCR assay for the combined detection and diagnosis of many clinically relevant herpes viruses in patient samples. The assay is quantitative and will both benefit patients as wells as molecular labs where the number of test for detection will be decreased. Using PCR assay is less costly then other methods and has been effectively used since January 1, 2004.

Market Value

Assay can be used for both detection and diagnosis and would benefit patients and molecular labs worldwide as it can detect many of the common clinically important Herpes viruses.

Features and Benefits

• Cost effective
• Fewer assays need to be run for diagnosis
• Quantitatively detects a many clinically important viruses
• Detection and diagnosis can be done in one test

Publications

• Josh Levitsky, Alison G. Freifeld, Susan Puumala, Kim
Bargenquast, Penny Hardiman, Catherine Gebhart, Lucy
Wrenshall, Alan Langnas, Andre C. Kalil (2007) Cytomegalovirus
viremia in solid organ transplantation: does the initial viral load
correlate with risk factors and outcomes? Clin Transplant 2007
DOI: 10.1111/j.1399-0012.2007.00778.x

Early Stage

US Patent Issued:

      7,442,505

UNeMed Corporation offers a variety of licensing options and collaborative development opportunities with the University of Nebraska Medical Center.