PITDC: Method of preparing an extract potent in anti-inflammation, anti-platelet aggregation and anti-fungal activity from Zingiber officinale, and pharmaceutical compositions containing said extract
A method of preparing an extract from Zingiber officinale,
which is potent in anti-inflammation, anti-platelet aggregation
and anti-fungal activity, which includes the following steps:
prepare a crude liquid from rhizomes of ginger by extraction
with an organic solvent or supercritical CO2 or by distillation
with steam; introducing the crude liquid to a reverse phase
chromatography column, and eluting the column with water,
a first eluent and a second eluent having a polarity weaker
than that of the first eluent but stronger than that of
chlorofrom, so that a first eluate resulting from elution of the
first eluent and a second eluate resulting from elution of the
second eluent are obtained; removing the first eluent and the
second eluent from the first eluate and the second eluate by
evaporation, respectively, so that a first concentrated eluate
and a second concentrated eluate are obtained as the potent
extract. The final product or the crude liquid obtained in the
first step may be incorporated into a pharmaceutical
composition together with a suitable carrier of diluent.
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