Biocompatible and biodegradable nanoparticles
Biocompatible and biodegradable nanoparticles designed to encapsulate drug allowing for its absorption and delivery
Mechanism of action
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Full description
The invention allows production of biocompatible and
biodegradable pseudolatex particles with a homogeneous
size below 140nm. The nanoparticles of the invention
advantageously show efficient immobilization of
proteinaceous drugs (peptide, proteins, or other sensitive
biopharmaceutical drugs) by preserving their activity and
allowing for their controlled release. The nanoparticles are
stable colloidal carriers against environmental attacks such
as pH modifications or freezing or freezedrying processes.
Drugs and drug combinations are adhered on/or incorporated
in nanoparticles which can then be applied in methods of
treating patients. Administration can be oral, intraperitoneal,
topical, intranasal or intravenous.
The drug which can be used according to the invention is a
low molecular lipophilic compound or polypeptide: diazepam,
antibiotics, anesthetics, antimitotics, enzymes, antigen
molecules (BSA), somatotropin, tetanus toxoid, influenza
virus, to name a few. Examples of treatments are clinical
applications such as diabetes and tumour treatment,
inflammation and intracellular infection treatment, adjuvant
for
vaccine, vaccine controlled delivery (HIV virus or influenza)
Patent information
PATENT STATUS:
Granted : EP, US, JP, CA
Type of business relationship sought
International license opportunities are available
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