Capsaicin, the active ingredient found in red-hot peppers, is used mainly for the relief of chronic pain of rheumatoid arthritis and osteoarthritis.
Project status: The capsaicin patch developed by LTS is a flexible, rectangular patch with rounded corners with maximal surface area of 300 cm2 (smaller patches are possible) Due to its textile backing layer, the patch is one-way stretchable. It consists of a self adhesive matrix, containing capsaicin, below 0.5% in concentration, and exhibits a pleasant heat sensation and good adhesion.The intensity of the heat sensation can be varied in either direction by changing the capsaicin concentration.
The current formulation was tested for stability over 3 years indicating a stable patch formulation at room temperature.
Competitive advantage: The main advantages of a topical capsaicin patch compared with available products on the market such as ointments or creams are:
Available for licensing. LTS will perform further development in collaboration with a partner. Further activities in the development of the patch include scale up to pilot plan production, validation and if required a clinical study in humans.
Head of Business Development
LTS Lohmann Therapie-Systeme AG is a world class developer and manufacturer of transdermal (TTS) and oral thin film (OTF) drug delivery systems and adhesive laminates.View profile
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