NovaSperse℠ is a novel cost-effective process used to create amorphous spherical nanoparticle formulations of pure, poorly soluble APIs to enhance solubility, improve bioavailability and enable all delivery routes. More
These mice manifest the same defects seen in people afflicted by autosomal recessive ichthyosis with hypotricosis so it can be an effective model for studying the role of matriptase in disorders that affect skin development. More
The compounds, peptides and nucleotides, are useful for the treatment of diseases such as premature aging syndromes, dyskeratosis congenita, neurodegenerative diseases, cancer and other pathologies. More
Topical application of DKK1 to non-palmoplantar skin induces the development of increased skin thickness, decreased pigmentation, and decreased hair growth. More
The Parasitology Laboratory is at the forefront of the battle against insects, mites and ticks, which can cause allergies, damage to the skin, and act as vectors of pathogenic micro-organisms. More
The laboratory is active in the field of synthesizing biologically active small molecules. The molecules can be heterocyclic and may also contain boron and phosphorus More
Lead Inventor: Angela M. Christiano, Ph.D. Problem or Unmet Need The lack of treatments available for people with absent, weak, or slow growing nails (because of inherited abnormalities or infection) is partly due to poor understanding of the molecular... More