Inventors have shown that, in human patients, the administration of anti-muscarinic agents produces a rapid, prolonged alleviation of depressive symptoms. More
Use of new bufadienolide derivatives were synthesized. These steroids have showed to affect cell growth, induce apoptosis and provoke unique changes in intracellular membrane traffic and endosomal pH. Of particular interest are the observations... More
Recent advances in pharmacology, molecular biology, and genetics on the serotonin system hold out the promise of the development of improved pharmacological treatment for some aspects of neurological diseases. More
Lead Inventor: Koji Nakanishi Problem or Unmet Need: Ginkgo biloba is a frequently used herbal remedy for increasing cognitive function in the elderly and Alzheimer's patients, treating vascular and neurodegenerative dementia, and improving circulation... More
Lead Inventor: Michael Terman Problem or Unmet Need: It is estimated that about 10 million Americans suffer from winter depression at a fully syndromal level, with another 25 million suffering at a milder subsyndromal level which is less debilitating and. More
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