A novel cyclized histatin-based peptide DB2-121 that is a potent new antifungal agent active against the clinically important Candida albicans and a number of other organisms. More
The present invention utilizes the characteristic chemical property of hydrazide groups on one reactant to react with aldehyde groups or cyanate esters on the other reactant with an improved conjugate yield of at least sixty percent. More
Invention can be developed as an inhibitor therapeutically or prophylactically against retroviral and non-retroviral infections, and can be used in combination with other anti-viral agents to treat patients who have drug-resistant virus. More
Uses of a p53 specific microRNA (miRNA): It has been reported that the tumor suppressive mRNA miR-34a (a downstream target of p53) is downregulated in HPV-infected primary keratinocytes. More