A strategy for artificially inducing the internalization of surface receptors, thereby blocking the effects of the ligands associated with that receptor More
These coding sequences have successfully been delivered to endothelial cells and tumor cells both in vitro and in vivo, and have demonstrated significant anti-tumor activity. More
A novel therapy for the suppression of cancer metastasis onset.Metastasis, the spread of tumor cells from the primary site to distant organ environments, is the leading cause of death from cancer. A key turning point in the course of cancer progression... More
Delivery of contrast material to tumor cells can be compromised by the abundance of perivascular stroma myofibroblasts that hinder transfer of materials from the vessels to the tumor cells. Evoking an alternate competing endocytic pathway using a novel... More
Novel molecules for the treatment of angiogenesis-dependent diseases.
Angiogenesis, the formation of new blood vessels, is implicated in the onset of a wide range of diseases such as age-related macular degeneration, corneal neovascularization and... More
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