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Triazolyl aminocyclitol derivatives acting as chaperones of the glucocerebrosidase enzyme, restoring its activity at micro and nanomolar concentrations. These compounds may have application as drugs in the treatment of Gaucher disease More
New aminocyclitol derivatives acting as chaperones of the mutated glucocerebrosidase enzyme, restoring its activity at nM and sub-nM concentrations. These compounds may have application as drugs to treat Gaucher disease, including the lethal type II More
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