A novel non-invasive method for using carbon-13 magnetization transfer effects to determine and evaluate in vivo aspartate transaminase (AST) activity and levels in an organ, as a biomarker of disease and certain neurological disorders. More
A number of specific PPLs, a group of prenylflavanone compounds, some novel, were isolated, identified and tested at as low as 0.04 μg/mL to be able to increase survival of neural stem cells, to promote neuronal growth with lengthening of neurite More
Two new compounds having HDAC (histone deacetylase) inhibition capability have shown the effect of inducing re-differentiation of human brain and breast cancer cells both in vitro and in vivo. More
These radioactive compounds have the very unique and unprecedented ability to bind very specifically and irreversibly to butyrylcholinesterase (BChE). More
2-arachidonylglycerol (2-AG) is used to inhibit tumor necrosis factor alpha (TNF alpha) and as a neuroprotector of the brain in closed head injury. 2-AG can be usedalso to reduce edema caused by closed head injury, to reduce neurological deficits... More
The present invention provides assays for the detection of human RFX4_v3 polymorphisms or deficiencies that may lead to the determination of an individual's risk of developing hydrocephalus. More
MDF004 and MDF005 are natural phenolic antioxidants that rescue neurons from cell death in acute injury and reduce neurological deficits caused by ischemic damage to the brain. More
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