Methods for improving pancreatic endocrine function and delaying the onset of diabetes by enhancing beta cell function using ligands and/or regulators of Notch receptors More
This invention relates to methods for manipulating the immune system using small interfering RNA (siRNA). Potential applications include the development of organ storage/reperfusion solutions and treatments for a broad range of disease indications. More
The technology provides methods for diagnosis and treatment of conditions such as cancer, diabetes, or other conditions that are influenced by AM levels. More
The most desirable feature of this new compound is its ability to specifically inhibit O-GlcNAcase without targeting the related hexosaminidase A (HEX A) and hexoaminidase B (HEX B) enzymes. More
Provision of access to DNA samples of 16 common diseases to conduct association studies of specific single nucleotide polymorphisms (SNPs) and specific diseases More
Diabetes mellitus, a metabolic disease caused by deficiency of insulin, displays a higher or lower level of glucose concentration in blood than normal range(80-120mg/dL). More
Name of the inventor: Domenico Accili Problem or Unmet Need: Type II diabetes is a very complex disease involving many tissues and several key protein components, two of which are insulin receptor and the transcription factor FoxO1. Recently, FoxO1 was... More
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