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Cripto-1 expression increases the expression of TNF-alpha in CD4+ T cells in tissues affected by chronic inflammatory disease. More
These hybrid antibody molecules can be engineered with a variety of small synthetic molecules, and the combination of immunogenic properties results in compounds with powerful target destruction or imaging capabilities. More
MGD3 monoclonal antibody binds human Dectin-1 with high affinity and regulates production of cytokines TNF-α and Interleukin-10. MGD3 has a potential therapeutic use on inflammatory diseases. More
Compositions and methods for treating immune related disease More
Experiments confirm that RPS3 is essential for normal expression of specific NF-kappaB target genes, including key physiological events that require p65. More
Grb2 SH2 domain signaling antagonists with enhanced binding affinity. More
Novel peptides have been developed that are useful to induce Autoimmune Anterior Uveitis (AAU) and to treat symptoms associated with Anterior Uveitis. Additional potential uses for these peptides include identification of specific antigenic or uveitogeni More
Anti-CD79 Antibody Offers Novel Approach to Therapy in Autoimmune Disease, Transplantation and Lymphoma More
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Therapeutic target
Immune related disorders del
Autoimmune disease (non-specific) del
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