The use of vitamin-drug formulations to (a) enable oral absorption of pharmaceutically active ingredients which are not normally absorbed in the GI tract and (b) enhance delivery of drugs to diseases such as cancer and rheumatoid arthritis. More
Identification and characterization of three (3) novel fully human monoclonal antibodies, which may be used to prevent binding of IGF-I to its concomitant receptor IGFIR, consequently, modulating diseases such as cancer. More
The present invention describes cytotoxic compounds with an intracellular target that can selectively enter tumor cells through specific receptors on the cell surface. More
US based researchers are seeking licensing partners for the further development of their antigen which is intended for the treatment of breast cancer but could also have applications in ovarian cancer and other malignancies. More
The technology describes the humanization of a murine anti-carcinoma antibody CC49 which has been shown to react with Tumor Associated Glycoprotein 72 (TAG-72), an antigen which is expressed on human breast, ovarian, colorectal, and other carcinomas. More
The present invention concerns a stable lipid assembly comprising a biologically active lipid having a hydrophobic region and a polar headgroup. These specific lipid assemblies comprise the biologically active lipid, ceramide, a lipid derivatized... More
A method of antitumor therapy is described in which administration of a chemotherapeutic drug, encapsulated in liposomes, is supplemented by administration of an immunostimulating cytokine. The cytokine is preferably also encapsulated in liposomes.... More
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