Through in vitro and in vivo tumor suppression experiments, the inventors have demonstrated that DLC-1 acts as a new tumor suppressor gene for different types of human cancer. More
An anti-mesothelin antibody of human origin has been generated; it has the ability to efficiently recognize mesothelin on the surface of cells, and induce ADCC in mesothelin-positive cells. More
New SS1P constructs include Pseudomonas Exotoxin A fragments and mutants with reduced immunogenicity, resulting in immunotoxins with greater efficacy. More
A novel method for determining the prognosis of a subject with adenocarcinoma in an organ and to aid in the selection of a specific therapeutic regimen. More