A novel non-invasive method for using carbon-13 magnetization transfer effects to determine and evaluate in vivo aspartate transaminase (AST) activity and levels in an organ, as a biomarker of disease and certain neurological disorders. More
Two new compounds having HDAC (histone deacetylase) inhibition capability have shown the effect of inducing re-differentiation of human brain and breast cancer cells both in vitro and in vivo. More
Experiments in vitro demonstrate that these novel SMO inhibitors potentially suppress the growth of cancer cells and inhibit the expression of the HH/PTCH pathway genes. More
Intravenously administered nanoparticles selectively cross the blood-brain barrier of brain tumors and accumulate within brain tumor cells but not normal brain cells More
This new technology distinguishes between cytostatic and cytotoxic compounds, thereby significantly reducing the time and cost required to screen anti-tumor agents. More
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