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On-Demand Protein Microarrays: In Vitro Assembly of Protein Microarrays
A DNA microarray that becomes a protein microarray on demand and provides an efficient systematic approach to the study of protein interactions and drug target identification and validation. More
Lentivirus Based Vector System for Gene Therapy Delivery
A retroviral vector system comprising a packaging vector and a transfer vector, and a method of using the vectors for gene therapy. More
Aerosolized Vaccines
Aerosolized immunogenic compositions that may prove useful for vaccination against respiratory infections and may provide a platform for generating mucosal antibody responses against other pathogens. More
Modified Sugar Substrates and Methods of Use
Methods and compositions for making and using functionalized sugars More
Insect Cell Production of Recombinant Adeno-Associated Virus that Produce Cytotoxic Gene Products and Applications for Solid Tumor Therapy
A new method for targeting solid tumors using gene therapy More
Construction of an Infectious Full-Length cDNA Clone of the Porcine Enteric Calicivirus RNA Genome
The development of an infectious cDNA clone is important because it enables the use of More
Human soluble FcRn and Beta2-microglobulin expressing vector
A vector to be used for transfection and purification of human soluble FcRn receptor More
HIV gp41-Membrane Proximal External Region Arrayed on Hepatitis B Surface Antigen Particles for HIV Diagnostic and Vaccine Applications
Multiple copies of the MPER of HIV-1 gp41 arrayed on HBsAg particles could significantly increase the immunogenic potential compared to monomeric molecules. More
Construction of Recombinant Baculoviruses Carrying the Gene Encoding the Major Capsid Protein, VP1, From Calicivirus Strains (Including Norovirus Strains Toronto, Hawaii, Desert Shield, Snow Mountain, and MD145-12)
Growth of these baculovirus recombinants in insect cells results in the expression of virus-like particles (VLPs) that are antigenically indistinguishable from the native calicivirus particle. More
Full-Length cDNA Clone Representing the Consensus Sequence of the RNA Genome of a Human Norovirus (strain MD145-12) that Encodes Biologically Active Proteins
The subject cDNA clone of the virus encodes proteins of the MD145-12 strain that, when expressed in vitro, exhibit properties that would be expected from those produced by the original infectious virus. More
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