The cultured autologous squamous epithelium, which differentiates into mucociliary epithelium after in vivo grafting, are remarkably effective in airway luminal reconstruction. More
Experiments in vitro demonstrate that these novel SMO inhibitors potentially suppress the growth of cancer cells and inhibit the expression of the HH/PTCH pathway genes. More
The various properties of this PE cell line differ from keratinocytes, which will provide a growth advantage to the PE cell lines during tumor promotion. More
These mice manifest the same defects seen in people afflicted by autosomal recessive ichthyosis with hypotricosis so it can be an effective model for studying the role of matriptase in disorders that affect skin development. More
This technology offers an alternative means to generate collagen and gelatin which are traditionally derived from animals including cows, pigs and also cadavers. More
Identification and characterization of a FNIP1 homolog, folliculin-interacting protein 2 (FNIP2), that interacts with folliculin, the protein encoded by the FLCN gene, which is responsible for the Birt-Hogg-Dube’ (BHD) syndrome. More