Retractable inhibitors controlled through polypeptide-protein interactions with the flexible peptide bridge that link the two binding fragments may represent an alternative approach to antidote-reversible anticoagulant therapy. More
Lead Inventors: Thomas Diacovo, Jianchun Chen Problem or Unmet Need: One major hurdle hindering antithrombotic drug development is the lack of an appropriate small animal model of thrombosis to test promising therapies, as in vitro models of thrombosis... More
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