Two new compounds having HDAC (histone deacetylase) inhibition capability have shown the effect of inducing re-differentiation of human brain and breast cancer cells both in vitro and in vivo. More
A novel non-invasive method for using carbon-13 magnetization transfer effects to determine and evaluate in vivo aspartate transaminase (AST) activity and levels in an organ, as a biomarker of disease and certain neurological disorders. More
The inactivation approach presented in this technology provides for a safe, non-infectious composition for vaccination against the corresponding agent. More
New pyridinic sulfonamide derivatives for the treatment and/or prevention of diseases such as inflammation, arthrosis, cancer and angiogenesis and for other pathologies in which they can play a role as COX-2 selective inhibitors. More
Researchers at the University of Edinburgh, led by Professor Peter Sadler, have developed a novel series of platinum prodrugs, which can be activated by light (photoactivated). More