A novel non-invasive method for using carbon-13 magnetization transfer effects to determine and evaluate in vivo aspartate transaminase (AST) activity and levels in an organ, as a biomarker of disease and certain neurological disorders. More
Transgenic mice for screening compounds with therapeutic potential against pain, hyper-thyroidism or obesity. These transgenic mice over-express DREAM, a transcriptional repressor More
Diabetes mellitus, a metabolic disease caused by deficiency of insulin, displays a higher or lower level of glucose concentration in blood than normal range(80-120mg/dL). More
The most desirable feature of this new compound is its ability to specifically inhibit O-GlcNAcase without targeting the related hexosaminidase A (HEX A) and hexoaminidase B (HEX B) enzymes. More