Out-licensing

A novel non-invasive method for using carbon-13 magnetization transfer effects to determine and evaluate in vivo aspartate transaminase (AST) activity and levels in an organ, as a biomarker of disease and certain neurological disorders. More

Two novel classes of compounds useful as radioligands for in vivo imaging of beta-amyloid peptides and plaques in humans More

Contrast agents for ultrasonic imaging, destruction of clots, ultrasound-induced permeability of blood vessels and other tissues, targeted drug delivery, or to enhance ultrasonic tissue ablation. More

A level set based method to determine, from a CT colonography (CTC) scan, the location of the colon serosal tissue boundary: After determining this location, the algorithm segments the entire colon wall at subvoxel accurate precision. More

Butyrylcholinesterase is commonly overexpressed in many types of cancer including ovarian cancer and gliomas. These compounds provide both therapeutic and diagnostic capabilities useful in the treatment of a variety of cancers. More

These microstructures can be engineered to appear as different effective colors when resolved using MRI as opposed to strictly grey-scale contrast of existing MRI agents. More

Parametric and non-parametric statistical methods that help distinguish changes in tissue state from background noise inherent in all MRI measurements. More