The present invention relates to osteoarthritis (OA) and methods of OA diagnosis and treatment via the findings of a genome-wide analysis of dysregulated genes in OA. More
Colorless molecule that will bind and enhance the differential surface charge on protein complexes: The molecule has been demonstrated to work as well as Coomassie blue but will not interfere in gel assays critical for most investigations. More
A simple blood based assay to identify diabetic patients who are likely to develop or have early stage diabetic nephropathy has been developed at King's. This has the potential to be used regularly at diabetic clinics. More
A new method for enhancing L-ASP activity by combining it with antagonists of asparagine synthetase - such as siRNAs, antisense nucleotides, antibodies or small-molecule inhibitors More
The primary function of ADAMTS-2 is the maturation of procollagen type I, II and III. Results obtained by in vitro testing, ex vivo model, and in vivo model support the hypothesis that ADAMTS-2 is an anti-angiogenic factor. More
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