Identification of three genetic markers in the ABCB1 gene that can be used to predict the degree of neutropenia and peripheral neuropathy that an individual will experience following paclitaxel treatment More
The technology overcomes some limitations of conventional YTHS by extending its ability to detect interactions of biological relevance to the cytoplasm and the plasma membrane. More
Through in vitro and in vivo tumor suppression experiments, the inventors have demonstrated that DLC-1 acts as a new tumor suppressor gene for different types of human cancer. More
Unique distinctions of this design over other CNT based methods: complete isolation of the CNTs from chemical reactions concomitant with probe immobilization and target capture, and the CNTs functioning only as charge sensors. More
Sensitive detection and characterization of macromolecular interactions in homogenous or heterogeneous solutions of biological and/or synthetic macromolecules More
Diagnostic and therapeutic methods are provided in this invention involving the correlation of polymorphic variants in MTHFD1 and other genes with relative susceptibility for various pregnancy-related and other complications. More
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