A fractionated herbal extract (STD052) demonstrating cholesterol/triglyceride lowering properties, purified down to a single active compound (STD07), a potential drug candidate for the treatment of GI disorders. More
This invention concerns a new approach to the treatment of rheumatoid arthritis (RA) by "tolerogenic vaccination" with small interfering RNA (siRNA) technology. More
New pyridinic sulfonamide derivatives for the treatment and/or prevention of diseases such as inflammation, arthrosis, cancer and angiogenesis and for other pathologies in which they can play a role as COX-2 selective inhibitors. More
The primary function of ADAMTS-2 is the maturation of procollagen type I, II and III. Results obtained by in vitro testing, ex vivo model, and in vivo model support the hypothesis that ADAMTS-2 is an anti-angiogenic factor. More
The present invention relates to osteoarthritis (OA) and methods of OA diagnosis and treatment via the findings of a genome-wide analysis of dysregulated genes in OA. More
The University of Edinburgh has developed a new method of screening for polymorphs and solvates of drug compounds that has potential to revolutionise the way polymorph screening is conducted. More