Out-licensing: Biotechnology & Immune Related Disorders

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Micro Fine, Dry Powder Pulmonary Drug Delivery Technology Suite

Researchers at the University of Western Ontario have developed a Pulmonary Drug Delivery Technology Suite comprised of two innovative inventions for the precision measurement and dispensing of micro fine, dry powders. More

Cripto-1 Represents a Biomarker for Chronic Inflammatory Diseases

Cripto-1 expression increases the expression of TNF-alpha in CD4+ T cells in tissues affected by chronic inflammatory disease. More

A NEW AEROSOL TREATMENT FOR ASTHMA USING A NON-STEROIDAL COMPLEX WHICH PREVENTS BRONCHIAL REMODELLING

Aerosolized pharmaceutical composition with low potential toxicity, significantly reducing airway inflammation and remodelling More

Protein (Biomolecule) Transduction Domain (PTD)

Rheumatoid arthritis More

Enhanced T-cell Activation by Costimulation: An Effective Immunotherapy for Cancer and Infectious Diseases

The present technology describes recombinant poxvirus vectors encoding at least three or more costimulatory molecules and TAAs. More

TNF-alpha Converting Enzyme Inhibitory Agents and Stimulatory Agents

This TACE inhibitory protein could be used as a new therapeutic agent against chronic inflammatory diseases that are mediated by TNF-alpha. More

Chitosan as a Universal Vaccine Adjuvant, Antigen Depot and Cytokine Depot

This technology is the first to show that subcutaneous administrations of chitosan and an appropriate antigen, with no other component, can be used for enhancing immune responses. More

Adoptive Immunotherapy with T Lymphocytes Engineered for Enhanced Survival

A method of transfecting isolated autologous T-Lymphocytes with endogenous cytokines, for example IL-7 and IL-15, to sustain an adoptive T-lymphocyte response without systemic toxicity. More

Cyclic Histatin Peptide Antifungal Agent

A novel cyclized histatin-based peptide DB2-121 that is a potent new antifungal agent active against the clinically important Candida albicans and a number of other organisms. More

Inhibitors of Ubiquitin E1

These novel pyrazolidinyl compounds can stabilize p53 and induce apoptosis in mammalian cells through selective inhibition of ubiquitin E1. More

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Industry sector: Biotechnology del
Therapeutic target: Immune related disorders del

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Industry sector: Assay systems; Diagnostic test systems; Gene therapy; Human diagnostics; Human therapeutics; Nanotechnology; Other; Research supplies; Stem cells
Therapeutic target: Adoptive immunotherapy; Amyloidosis; Autoimmune disease (non-specific); Chronic fatigue syndrome; Chronic granulomatous disease; Chronic immunosuppression; Gout; Graft versus host disease; HIV/AIDS; Immune disorder (non-specific); Immune thrombocytopenic purpura; Immunomodulation; Immunostimulation; Immunosuppression; Lupus erythematosis; Myalgic encephalomyelitis; Myasthenia gravis; Neoplastic disease; Organ transplant rejection; Rheumatoid arthritis; Servere combined immunodeficency; Sjogren's syndrome; Systemic sclerosis; Transplant rejection; Xenotransplantation
Development phase: Early Stage; Preclinical; Phase I; Phase I/II; Phase II; Phase III; Phase III/IV; Preregistration; Registered

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