In addition to anti-tumor activity, these compounds have been shown to be potent irreversible inhibitors of P-glycoprotein, a member of the ABC transporter protein family that has a major role in conferring multi-drug resistance. More

Neomics has found a very promising target, AIMP2/AIMP2-DX2 for siRNA therapy application to tumoric lung cancer cells and we intend to focus the remaining resources on developing through clinical trials, the siRNA therapy as a first priority More

Through in vitro and in vivo tumor suppression experiments, the inventors have demonstrated that DLC-1 acts as a new tumor suppressor gene for different types of human cancer. More

A novel temporal TGF-beta gene expression signature that predicts HCC patient clinical outcomes More

HCC cells treated with CSN5 siRNAs inhibited HCC progression and increased apoptosis in vitro and in vivo suggesting that CSN5 is an effective target for the development of cancer treatments. More