In addition to anti-tumor activity, these compounds have been shown to be potent irreversible inhibitors of P-glycoprotein, a member of the ABC transporter protein family that has a major role in conferring multi-drug resistance. More

Methods and assays which may be used to diagnose and follow the progression of cancers associated with c-Met expression More

Active ingredient for the treatment of bacterial infections and/or renal cancer diseases More

Dendritic cell (DC) generation and manipulation technology for the development of a cancer vaccine and rheumatoid arthritis (RA) therapeutics. Based on DC manipulating technology, Creagene is developing DC-based cancer vaccines against renal cell car More

Peptides and antigen epitopes specific for RCC for use in the diagnosis, vaccination, or adoptive infusion of antigen specific T cells to treat patients with metastatic RCC More

This T-cell receptor recognizes a number of human kidney tumors and is not limited to use in patients with specific MHC types. More

This invention discloses peptides for use in immunotherapy of tumors. More

The invention relates to methods of quickly and accurately diagnosing renal cellular carcinoma (RCC) and monitoring renal tissue health as well as RCC treatment. More

Identification and characterization of a FNIP1 homolog, folliculin-interacting protein 2 (FNIP2), that interacts with folliculin, the protein encoded by the FLCN gene, which is responsible for the Birt-Hogg-Dube’ (BHD) syndrome. More