The University of Edinburgh has perfected a genetic engineering strategy in mouse embryonic stem cells to replace large regions of mouse chromosomal sequences (>100kb) with the corresponding human syntenic region. More
Researchers at the University of Edinburgh have identified two protein domains (MBD and CxxC) proven to isolate methylated and non-methylated CpG islands (CGIs), respectively. More
The advantage of this drug delivery system is the ability to directly target specific skeletal sites of disease, while also being able to administer the lowest, clinically effective dose possible, thereby lowering the potential for harmful side effec More