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Pharmalicensing
is a division of
UTEK Europe Ltd
UTEK Corporation
Companies

Innocoll, Inc.

Innocoll, Inc.
Specialty pharmaceutical and drug delivery company engaged in the research and manufacture of collagen-based technologies for local drug delivery, surgical implants, advanced wound care and oncology.

The company in detail

Profile

Innocoll is an international, specialty pharmaceutical and drug delivery company engaged in the research, development and manufacture of innovative collagen based medical products ulilizing the company's drug delivery technology platforms (CollaRx®and LiquiColl®). These technologies are fully biodegradable and designed for the localized, site-specific delivery of a wide variety of drugs and are specifically intended to minimize systemic exposure and associated side effects.

Localized delivery provides a way of targeting the optimum dose of a drug to precisely where it is needed, rather than distributing excessive and sometimes unnecessary concentrations throughout the body via the systemic circulation. Such delivery systems can enhance a drug's efficacy and reduce unwanted side effects compared to oral or intravenous administration, particularly when targeting poorly vascularized areas such as bone and chronically infected wounds. Localized delivery can also be used as an adjunct to systemic therapy, such as in the prevention of infection or management of pain.

The parent company, Innocoll Inc., has three operating divisions:

• Drug Delivery and R&D Division (Innocoll Technologies)

• Sales and Marketing Division (Innocoll Pharmaceuticals)

• Commercial Manufacturing Division (Syntacoll)

Innocoll Technologies is responsible for the development of new products based upon the proprietary CollaRx and Liquicoll technologies as well as research into new collagen-based pharmaceutical products and medical devices. Internal programs are focussed on treatment and prevention of surgical site infections, advanced wound care, post-operative pain management, prevention of surgical adhesions and oncology. We are also seeking co-development partnerships with pharmaceutical and biotechnology companies interested in using our technologies to develop first-line products or localized delivery line extensions of existing brands.

Innocoll Pharmaceuticals is responsible for establishing and overseeing collabrations with Innocoll's marketing partners. The lead marketed product, Gentamicin Surgical Implant (Collatamp G), is a leave-behind surgical implant indicated for the treatment and prevention of post operative infections. The product is promoted to surgeons across a broad range of surgical specialities, including orthopedic, thoracic, abdominal, and vascular procedures, where there is often increased risk of post-operative infection or where such infections can lead to severe complications. It is currently marketed in more than 30 territories under various trade names throughout most of Europe and other "rest-of-world" countries in Latin America, Middle East, Asia and Africa. Innocoll is also developing Collatamp G for the US market where it is currently in Phase 3 clinical trials for the prevention of surgical site infections and Phase 2 trials as a topical treatment for infected diabetic foot ulcers.

Syntacoll AG (Switzerland) is the holding company for Innocoll's two commercial manufacturing facilities, Syntacoll GmbH in Saal, Germany, and Syntacoll Pty in Midrand, South Africa. An additional manufacturing facility is planned at Innocoll Technologies HQ in Roscommon, Ireland.

Partnering strategy/interests

Out-license of internal pipeline products for the prevention of surgical site infections, treatment and prevention of infected diabetic foot ulcers, advanced wound care, prevention of surgical adhesions and oncology. Partnerships with pharmaceutical and biotechnology companies interested in localized drug delivery of their proprietary molecules.

Out-licensing

Collagen-based dressings for wound management More
Collagen-based biodegradable matrices for localized drug delivery More
Indicated for the treatment and prevention of diabetic foot ulcers. More
Surgical implant for treatment and prevention of post-operative infections More
Gene targeting and localized delivery of anti-neoplastic agents More
Collagen-based adhesion barrier for the prevention of surgical adhesions More

R&D

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Deals

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Press Releases

(18th Jun 2009) Innocoll Announces Provisional Findings from its Three Phase 2 Clinical Trials Investigating CollaRx(R) GENTAMICIN TOPICAL for the Treatment and Prevention of Diabetic Foot Infections More
(31st Mar 2009) Innocoll, Inc. Files 510 (k) application for CollaRx Lidocaine Sponge More
(19th Mar 2009) Innocoll Announces Dosing of Last Patient in Second US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Colorectal Surgery Patients More
(16th Mar 2009) Innocoll Announces Dosing of Last Patient in US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Cardiac Surgery Patients More
(17th Nov 2008) Innocoll Receives Fast Track Designation for Gentamicin Surgical Implant More
(25th Aug 2008) BAXTER ANNOUNCES LICENSING AGREEMENT FOR INNOCOLL’S GENTAMICIN SURGICAL IMPLANT IN THE UNITED STATES More
(8th Aug 2008) Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx® BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain More
(28th Jul 2008) Innocoll Announces Dosing of First Patient in a Third US Phase 2 Clinical Trial to Investigate CollaRx® BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain More
(21st Jul 2008) Innocoll Appoints Anthony H. Wild Ph.D. to Its Board of Directors More
(30th Apr 2008) Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx® GENTAMICIN TOPICAL for the Prevention of Diabetic Foot Infections More
More press releases

Senior management

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Contact details

Ms Veronica Kelly
Marketing Executive
Innocoll Pharmaceuticals

Contact directly

Full contact list

Head office

Innocoll, Inc.
Midland Innovations Centre
Dublin Road
Athlone
Co. Westmeath
Ireland

Full offices list

Company figures

Formed: 2004
Number of employees: 130

Related categories

Industry sector
Animal health / Medical device
Animal health / Pharmaceutical
Biotechnology / Gene therapy
Drug delivery / Parenteral
Drug delivery / Topical
Drug delivery / Parenteral / Implant
Drug delivery / Parenteral / Sustained release
Drug delivery / Topical / Dermatological
Drug discovery / Bioinformatics
Medical device / Therapeutic device
Medical device / Therapeutic medical equipment / Surgical products
Pharmaceutical / Prescription
Pharmaceutical / OTC/Non-Prescription
Pharmaceutical / Generics
Therapeutic target
Accident and Trauma / Bone fractures
Accident and Trauma / Burns
Accident and Trauma / Hemorraghic trauma
Accident and Trauma / Tissue grafting
Accident and Trauma / Wound closure/surgical adhesive
Accident and Trauma / Wound/ulcer healing
Cardiovascular / Treatments / Cardiovascular surgery
Cardiovascular / Cardiovascular disorder (other) / Diabetic cardiovascular disease
Central Nervous System / Pain / Anesthesia
Central Nervous System / Pain / Pain management general
Central Nervous System / Pain / Pain, back upper/lower
Central Nervous System / Pain / Pain, chronic
Central Nervous System / Pain / Pain, inflammatory
Dermatological
Dermatological / Wound healing
Dermatological / Burns
Dermatological / Ulcer, diabetic
Hospital and Surgery / Adhesion
Hospital and Surgery / Anesthesia
Hospital and Surgery / Bleeding
Hospital and Surgery / Infection control
Hospital and Surgery / Surgery (other)
Hospital and Surgery / Tissue grafting
Hospital and Surgery / Wound closure
Metabolism / Diabetic complications
Musculoskeletal / Trauma, physical
Musculoskeletal / Skeletal / Bone repair/regeneration
Oncology / Bladder cancer
Oncology / Bone cancer
Oncology / Brain cancer
Oncology / Breast cancer
Oncology / Colorectal cancer
Oncology / Colorectal cancer
Oncology / Colorectal cancer
Oncology / Ovarian cancer
Oncology / Prostate cancer
Oncology / Treatments / Chemotherapy
Oncology / Cancer side effects / Metastasis
Oncology / Colorectal cancer / Rectal cancer

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