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University of Arkansas for Medical Sciences

University of Arkansas for Medical Sciences
Medical School - Teaching Hospital - Research Institution

The company in detail

Profile

The University of Arkansas for Medical Sciences (UAMS) is the State’s only comprehensive academic health center, with five colleges, a graduate school, a new 540,000-square-foot hospital, six centers of excellence and a statewide network of regional centers. UAMS has 2,652 students and 733 medical residents. Its centers of excellence include the Winthrop P. Rockefeller Cancer Institute, the Jackson T. Stephens Spine & Neurosciences Institute, the Myeloma Institute for Research and Therapy, the Harvey & Bernice Jones Eye Institute, the Psychiatric Research Institute and the Donald W. Reynolds Institute on Aging. It is the state’s largest public employer with more than 10,000 employees, including nearly 1,150 physicians who provide medical care to patients at UAMS, Arkansas Children’s Hospital, the VA Medical Center and UAMS’ Area Health Education Centers throughout the state. Visit www.uams.edu or www.uamshealth.com

The largest-ever research grant earned by the UAMS has reached 17 faculty members dedicated to clinical and translational research. 

The UAMS Center for Clinical and Translational Research (CCTR) recently awarded more than $1.1 million to faculty dedicated to pursuing clinical and translational research in two separate programs. The CCTR Pilot Study program awarded more than $973,000 to 15 investigators across nine UAMS departments, while the KL2 Mentored Clinical Research Scholar program will provide nearly $200,000 of support for two winners. 

The UAMS CCTR is one of 46 medical research institutions working together as a national consortium to improve the way biomedical research is conducted across the country. The consortium, funded through Clinical and Translational Science Awards (CTSA), shares a common vision to reduce the time it takes for laboratory discoveries to become treatments for patients, and to engage communities in clinical research efforts. It also is fulfilling the critical need to train a new generation of clinical researchers. The CTSA program is led by the National Center for Research Resources (NCRR), part of National Institutes of Health (NIH).

UAMS BioVentures serves as the Technology Licensing Office, spin-out business accelerator, and the portal to all of the University's intellectual property and economic development programs. For more information, please visit www.uams.edu/bioventures or contact Michael G. Douglas, PhD mdouglas@uams.edu or Charlie Cook at (501) 686-6696 – e-mail CACook@uams.edu

Partnering strategy/interests

The University of Arkansas for Medical Sciences, through its Technology Licensing Office, UAMS BioVentures, is seeking global, commercial partners to out-license its' innovations for the purpose of taking its discoveries to the world's medical and healthcare market places.

Out-licensing

Acetaminophen-protein Adduct Dipstick: rapid, sensitive and specific diagnostic device for point-of-care determination of acetaminophen toxicity More
Acute Renal Failure Target - Calcium Independent Phospholipase A2 More
Overexpressed in Werner's Syndrome Fibroblasts More
Alzheimer's disease and other Neurodegenerative Conditions More
Customized laser skin treatment for superficial tumors, hair removal, Port-Wine Stain and other superficial vascular disorders. More
Cardiovascular physiology and atherosclerosis - prevention of cardiovascular complications in patients with renal failure or increased carbamylation. More
Protein Targeting, Hypoallergenic Food Development, and Allergy More
Novel agents capable of reaching remote cellular sites More
Derivatives of Butyric Acid and Uses Thereof - treatment of autoimmune More
An immunoassay for the detection of CA125 utilizing the monoclonal antibodies More
Tumor Biology - Therapeutic sequestering tumor cells growth and diagnostic as a tumor specific marker More
Transmembrane Serine Protease Overexpressed in Ovarian Carcinoma More
Adjuvant therapeutic approaches and targets to improve remission in breast and melanoma cancers More
Extracellular Serine Protease Overexpressed in Breast and Ovarian Carcinomas More
Diagnosis of functional heart disease and heart disease prognostication with emphasis on the multifractal alpha, the Levy flight analysis and the key discrete wavelet smoothing. More
Therapeutic agents for neurodegenerative disease, such as amyotrophic lateral sclerosis (ALS) More
An expression array diagnostic tool to predict survival in cancer patients, as well as, composition and methods to induce the predictive gene expression profile More
Activation of Raf-1/MEK-1/2/p42MAPK Alone Is Sufficient to Induce LDL Receptor Expression More
P38MAPK Inhibitor for Elevation of Hepatic LDL Receptor Levels More
Application: Colposcopy - Foot-operated Focusing Device for Floor Stand Mounted Instruments More
Protection against injury to organs or tissues during pre-transplant storage and transport More
Novel peptides have been developed that are useful to induce Autoimmune Anterior Uveitis (AAU) and to treat symptoms associated with Anterior Uveitis. Additional potential uses for these peptides include identification of specific antigenic or uveitogeni More
Transgenic/genetic manipulation of mosquitoes and pest insects to control their impact on agricultural crops and human populations. More
Molecular Cloning and Characterization of Cyclin G1 Binding Protein1 More
Treatment of Skin and Epithelial Tumors Using Intralesional Injection of Combined Antigens More
A device and methods for the non-invasive manipulation and detection of target objects such as cells, pathogens, microparticles, and nanoparticles in vivo using an external magnetic field. More
Improvements in anticancer treatments More
Potential to extend the development of vaccines against previous unavailable HPV viral types. More
Generation of new vaccines against rare epitopes of HPV to block viral infection and prevent cervical cancer. More
Preventative vaccine, source of antigens for dendritic cell immunotherapy to treat cervical cancer More
Dynamic treatment simulation software system for Intensity Modulated Radiation Therapy (IMRT) prior to the initiation of actual therapy More
An Endothelial lined Stent for Rapid Endothelialization and Preventing Restenosis More
Genetic cloning and sequencing of a novel IL-17 receptor-related gene More
Pneumatically measures uterine contractions during pregnancy, labor and delivery. More
Novel diagnostic and prognostic gene array classification system More
Non-primate animal model to several human infectious diseases More
Expression of Genes in Heterologous Hosts More
Diagnostic and/or Therapeutic Tool to modulate cell development and function More
Different myeloma tumor cell lines and their expansion for use in drug screening and research More
Human papilloma virus type 57 (HPV 57) antigen in combination with Canada antigen elicits L1-specific T-cell responses and complete resolution of warts More
Use of Human Protein C for Intraocular Fibrin and Inflammation Prevention More
Method of Measuring by Gas Dilution Residual Lung Volume in Infants More
Growing mesenchymal stem cells that retain their undifferentiated properties More
Contrast agents for ultrasonic imaging, destruction of clots, ultrasound-induced permeability of blood vessels and other tissues, targeted drug delivery, or to enhance ultrasonic tissue ablation. More
Precise and focused control of temperature mediated therapy and “triggering” deliverables in situ. More
Nutritional intervention to abrogate the adverse effects in diabetes-related pregnancy More
Metabolomic assessment of the different Cytochrome P450 and UDP-Glucuronosyltransferase contributions to Warfarin Metabolism in individual patients More
Method of producing infectious papillomavirus in vitro and methods of making recombinant papillomavirus for vaccines More
Analytical methods for screening new drug candidates More
identifying and quantifying specific HAT activity at the lysine being targeted by the HAT for covalent modification More
Specific therapeutic target on platelets for blocking inflammatory diseases of the joint: “collagen microparticle footprint” More
Rapidly (less than 24 hours) diagnose MOTT infections in humans or animals More
In-home device to induce cycling motion in patients who have little or no motor control of their legs - increasing muscle mass and decreasing hyperreflexia More
Separation matrices that are used in combination to separate molecules on the basis of chirality and general physio-chemical properties of the molecule of interest More
Application: Safer and More Efficient Gene Therapies More
Biomimic prenatal and postnatal maternal-to-infant transfer of clinical monosaccharides for improved neurologic development and immunologic functions More
A novel and simplified methodology for growth and analysis of biofunctions with applications in the fields of pharmocogenomics and neurodevelopment and neurotoxicology. More
Improved dermatome designs having on-the-fly width and depth adjustability and improved performance for harvesting skin and burned tissue over surfaces of varying widths, depths, and skin quality. More
The proposed invention will provide a competitive advantage to any company or organization involved with the regulation of gene expression, cancer research, rational drug design, or any research and development More
Novel nonpalpable lesion detection procedure using hematoma - directed ultrasound and imaging. More
Novel method to quantify polymorphisms in electropherograms, a new approach to the identification of ambiguous DNA sequence reads and its automation More
A Unique Fragment of Parathyroid Hormone Related Protein Predicts Breast Cancer Metastasis To Bone More
A Unique Fragment Of Parathyroid Hormone Related Protein Predicts Breast Cancer Metastasis To Bone. More
Novel tocopherol and tocotrienol compounds that show increased efficacy over known radiation protection compounds while also exhibiting improved bioavailability and delivery as compared to previously-developed tocopherol derivatives. More
Novel Stilbenoid Derivatives and Methods of Their Use to Modulate Cannabinoid Receptor Activity or Scavenge Reactive Nitrogen Species More
Prevents oral trauma to surgical or long term ventilated patients due to insertion of endotracheal tube; additionally this novel device is beneficial in endoscope labs for both bronchoscope and transesophageal echocardiogram (TEE) procedures. More
Regulation of key transcriptional elements in the development and aging of heart muscle More
Surgical device, a catheter that enables a connection between the pancreatic duct and small bowel. More
Abdominal surgical closure device More
Thalidomide has been successfully used to successfully treat myeloma patients however, patients with high IL6R expression levels via gene expression profiling, do not benefit from the use of this drug. Therefore, the use of anti-IL6R therapies in combina More
drug delivery - a novel and effective method for the microencapsulation of small peptides that allows their use and controlled release over a time frame of several months. More
Cancer treatment, including vaccines, targets for immune stipulation, drug, or biological modifier delivery More
Computerized decision making information system to direct the orders for patients sustaining multiple rib fractures. More
Gene array analysis and genetic testing uncovering a TP53 genetic deletion in multiple myeloma patients in combination with the use of risk-adapted therapy that incorporates thalidomide with bortezomib vastly improves patent outcomes. More
when used in combination with other drugs these UGT inhibitors act to significantly enhance efficacy antiviral therapeutics that require UGT's for their systemic clearance. More
Ref: Molecular Microbiology (1999) 33, 1, 307-316 More
A device to position the arms of patietns during prolonged surgical procedures, to protect against nerve damage and also provide access to IV sites. More
Screening tool for the detection of breast and other cancers More
a powerful Anti-Inflammatory pharmaceutical composition for use in established Allergic Contact Dermatitis More
Method for Reducing Radiation Toxicity More
A gene expression profile (GEP) model has been developed for predicting cytogenetic abnormalities and thus disease progression across various types of cancers using DNA copy number analysis More
Mycobacterium Specific Tuberculosis Diagnostic Testing More
Cancer - Novel Cell Surface Proteolytic Activity (Proteases) in Carcinogenic Tissues More
Accurate placement of catheter needles More
Compositions and methods for targeted therapeutic release of encapsulated materials from multi functional liposomes at the site of a solid tumor or a diseased site using ionizing and non-ionizing radiation, a process called conformal Intensity Modulated R More
A multi-faceted invention that has identified novel compositions that may be useful for pharmacological, diagnostic and research development for more effective pain control. An in vitro enzymatic process that produces novel glucuronyl derivatives of canna More
Exogenous Type IV Collagen and combinations promote recovery of cellular function following sublethal toxic injury and renal disease More
Novel Surgical Clips for Vascular Bypass and Tissue Grafts for Vascular surgery, vascular grafts, sutureless anastomosis and bypass surgery More

Deals

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Press Releases

(9th Dec 2011) Signal Genetics to launch second generation Myeloma product, MyPRS Plus More
(24th May 2010) Little Rock, Arkansas Technology Task Force makes key gains with Tech Parks and Association Support More
(24th May 2010) University of Arkansas for Medical Sciences (UAMS) unveiled 22 of its most commercially promising startups and research discoveries to venture capitalists from coast to coast. For additional information Contact Dr. Mike Douglas at (501) 686-6696 or e- More
(24th May 2010) UAMS Arkansas BioVentures Startup Inks Deal With New York Drug Store Chain More
(24th May 2010) The University of Arkansas for Medical Sciences, through its Technology Licensing Office, UAMS BioVentures, is seeking global, commercial partners to out-license its innovations for the purpose of taking UAMS discoveries to the worlds medical and healthca More
(19th Mar 2010) LITTLE ROCK – The concept behind a unique program that saves Arkansas millions of dollars in Medicaid drug costs has spawned a new startup company through the University of Arkansas for Medical Sciences (UAMS) BioVentures. More
More press releases

Contact details

Mr. Christopher Fasel
Associate Director or Licensing
UAMS BioVentures - TLO

Contact directly

Full contact list

Head office

University of Arkansas for Medical Sciences
UAMS BioVentures
Technology Licensing Office
4301 West Markham Street #831
Little Rock
Arkansas
72205-7199
Arkansas (USA)

Company figures

Formed: 1879
Number of employees: 9600

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