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Pharmalicensing Ltd
is a division of
UTEK Corporation
Companies

National Research Council Biotechnology Research Institute

National Research Council Biotechnology Research Institute
NRC-BRI's Health and Bioprocess Sectors promote and conduct innovative collaborations, services and technology transfers with the biotechnology and pharmaceutical industries.

The company in detail

Profile

The Biotechnology Research Institute of the National Research Council Canada (NRC-BRI) is the largest research facility devoted to biotechnology in Canada. Through its Health, Bioprocess and Environment sectors, the Institute promotes, assists and conducts leading-edge R&D collaborations, services and technology transfers with the biotechnology and pharmaceutical industries. The expertise of NRC-BRI's multidisciplinary research teams in life sciences, forms a continuum that includes drug discovery, bioprocess development and scale- up. Committed to the practical applications of new knowledge, NRC-BRI's scientific excellence, extensive infrastructure, and outstanding track record in drug discovery and development help reduce the technological risks that its partners encounter. NRC-BRI's Health Sector is highly involved in developing cancer and infectious disease diagnostics and therapies. The Health Sector research focuses on the identification of molecular disease targets through the discovery and design of lead drug compounds. NRC-BRI's Bioprocess Sector is specialized in the production and purification of recombinant proteins from prokaryotic or eukaryotic expression systems. The Sector scientists and engineers utilize their world-class R&D expertise and facilities to assist pharmaceutical and biotechnology companies in the development, optimization, scale-up of bioprocesses and the production of bioproducts.

Partnering strategy/interests

NRC-BRI offers a range of opportunities for collaborations, partnerships, fee for service, technology licensing and laboratory space rental. NRC-BRI's partners include national and international biotechnology and pharmaceutical companies, universities and other governmental institutions. R&D: - Cancer and Infectious Diseases - Genomics and Proteomics - Molecular & Structural Biology - Biopharmaceutical Development - Bioprocesses Scale-up - Eco-efficient Industrial Production - Sustainable Industrial Process - Environmental Protection - Biochemical Engineering - Biomass Conversion - Bioremediation - Pathogens Detection SERVICES: - Laboratory Space Rental (IPF) - HTS Facility - Microarray Facility - Custom Antibodies Facility - Custom Peptides Facility - Flow Cytometry Facility - Microscopy/Imaging Facility - Biopharmaceutical Pilot Plant - Biotreatability Facility - Environmental Pilot Plant - Biacore Facility

Out-licensing

High yield and low cost protein production in a few days to a couple of weeks (mg or g of protein). Production of proteins, including antibodies, for High-throughput screening assays, antibody generation and structure-activity analyses. More
Direct thrombin inhibitors designed for improved safety/efficacy profile. Peptide inhibitors suitable for cost-effective recombinant production.Anti-thrombin peptides that can be fused to homing peptides for targeted delivery or fused to markers. More
This method provides an efficient tool for rapid and precise identification of the molecular formula of small molecules, with some characterization of sub-structures, without a cumbersome process of compound isolation. More
Retractable inhibitors controlled through polypeptide-protein interactions with the flexible peptide bridge that link the two binding fragments may represent an alternative approach to antidote-reversible anticoagulant therapy. More
This technology provides a vector and a cell line that enables easy production of replicant. More
Modified versions of these tetracyclines were developed for applications directed toward the specific inhibition of calpains More
This rapid and precise on/off switch regulate the expression of transgenes in mammalian cells More
Novel carrier proteins for the production of small or large peptides as recombinant fusion proteins. More
The present invention provides a potent inhibitor of protein glycation and AGEs formation that is particularly advantageous for eye-drop delivery in the prevention and treatment of diabetes- and age-related pathologies. More
Mammalian cell-based reverse two-hybrid system to screen and identify drugs having the ability to disrupt the interaction between two candidate proteins. More
The cumate-inducible expression system allows turning on the expression of a given protein only when needed. More
This technology presents key improvements in expression vectors, serum-free media and process of a system for transient gene expression in human cells that have significantly increased the ease and yield of r-protein production. More
Delivering high performance at low cost, this sterilizable probe allows monitoring real-time fermentation processes. More
Enzymatic production of a broad range of biosurfactants including generation of molecules that cannot be prepared using chemical synthesis. More
The technology overcomes some limitations of conventional YTHS by extending its ability to detect interactions of biological relevance to the cytoplasm and the plasma membrane. More

Deals

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Head office

National Research Council Biotechnology Research Institute
6100 Royalmount Avenue
Montreal
Quebec
H4P 2R2
Quebec

Tel:  +1 514 496 6100
Fax: +1 514 496 5007
www | email

Contact details

Mr. Yves Quenneville
Business Development Officer
Industrial Affairs
Request more information

Company figures

Formed: 1987
Number of employees: 500

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