With many treatments available, the pipeline for new drugs to treat this enigmatic disease is thin.

As with many neurological conditions, researchers have identified many possible causes, but no cures, for epilepsy, a disorder characterized by abnormal discharges of nerve cells, or neurons, in the brain. These discharges—where many neurons fire together at high frequency—cause seizures in which an affected person may experience convulsions, alteration or loss of consciousness, or muscle jerking (myoclonus).

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Linked with permission from Modern Drug Discovery, November 2004, 7(11), pp 21-23. Copyright American Chemical Society

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